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Population genomics for biodiversity conservation: Insights from the Swiss pilot study for monitoring genetic diversityNARA Subscribed
Genetic diversity is the raw material of evolution and is essential for adaptation and survival. Concerted efforts have been made under the Kunming-Montreal Global Biodiversity Framework (GBF) to incorporate intraspecific genetic diversity into national monitoring efforts. Much emphasis has been put on non-genetic proxies of genetic diversity, due to the limited amount of genetic data currently available on species and their p...
Gait kinematics during forward and backward locomotion in the Ansell’s mole-rat (Fukomys anselli)NARA Subscribed
Subterranean mammals have often been reported to habitually walk backwards both in the wild and in captivity. However, quantitative studies on this unusual behavior are sparse. For the present work, we collected video footage of spontaneous and induced forward and backward locomotion in captive Ansell’s mole-rats ( Fukomys anselli; family Bathyergidae). Based on that, analyses of spatio-temporal gait parameters (speed, stride...
Life‐history data are often lacking for exploited elasmobranchs, jeopardizing proper management and conservation measures for this vulnerable group. Herein, we provided age and growth estimates for the groovebelly stingray ( Dasyatis hypostigma ), a medium‐sized, heavily exploited batoid endemic to the southwestern Atlantic Ocean. Ages were estimated from vertebral centra, including 201 males and 71 females, with sizes varying...
Local and Landscape‐Level Environmental Conditions Drive Habitat Selection Across Terrestrial Mammal SpeciesNARA Subscribed
Aim Animal movements are a fundamental process affecting communities and ecosystems. Quantifying habitat selection across species and habitats is key for understanding how animals respond to environmental change. Currently, we lack comparative studies that examine how habitat selection varies across species traits and landscapes. We aim to quantify global patterns of habitat selection to help understand the fundamental drivers...
The Impact of Pleistocene Glacial Cycles on the Evolutionary Diversification of the Arctic‐Alpine Silene acaulis Species ComplexNARA Subscribed
Arctic‐alpine species are highly sensitive to long‐term temperature changes and associated glacial cycles due to their occurrence in cold environments to which they are adapted and spatially restricted. Unravelling their evolutionary responses to past climatic fluctuations can provide new insights into their diversification. In this study, we investigated the evolutionary history of the Silene acaulis species complex and how i...
Adaptation and validation of a gastrointestinal panel to detect diarrheal virus pathogens on a high-throughput qPCR systemNARA Subscribed
With around 2 billion cases each year, infectious gastroenteritis remains a worldwide health problem. A major cause of acute gastroenteritis is infection with enteric viruses, which often leads to hospitalization in children and immunocompromised people. We adapted and validated a gastrointestinal qPCR panel, which simultaneously detects the most common enteric viruses: Norovirus GI and GII, Rotavirus, Adenovirus, Sapovirus, A...
Pelagic sharks target long‐lived, retentive anticyclonic eddies in the Northwest Atlantic OceanNARA Subscribed
Open ocean ecosystems represent the largest habitat on Earth and are highly dynamic in time and space. Mesoscale eddies are a primary driver of this variability and serve a key structural role in ocean ecosystems. Eddies modulate marine biodiversity beyond their impacts on plankton, influencing many ecologically and commercially important predators that may preferentially occupy anticyclonic eddies. However, how animal‐eddy in...
The abscopal effect in metastatic lung cancer: a retrospective analysis of combined radiotherapy and immunotherapyNARA Subscribed
Background The abscopal effect (AbE) refers to the regression of non-irradiated tumors following localized radiotherapy (RT), suggesting a systemic immune-mediated response. The combination of RT with immunotherapy (IO) has been proposed to enhance the AbE by overcoming RT-induced immunosuppressive mechanisms, but robust evidence, specifically in non-small cell lung cancer (NSCLC), is lacking. This study aimed to determine the...
Ecological modelling for transformationNARA Subscribed
Introduction of immune checkpoint inhibitors (ICI) has improved overall survival (OS) for advanced non-small cell lung cancer (NSCLC). However, responses differ greatly amongst patients. Additional radiotherapy (RT) may promote tumor-specific immunity and synergize with ICI to improve tumor control. The multicenter phase II FORCE trial evaluated safety and efficacy of nivolumab with additional palliative radiotherapy (5 × 4 Gy...