Anchoring systems for deep-water floating structures must withstand complex, hydro-mechanical (H-M) coupled uplift forces throughout an operational life extending over decades, yet fundamental understanding of this complicated H-M behavior remains insufficient. This paper presents a comprehensive review of H-M coupled foundation–seabed interactions under uplift loading. Key experimental findings are synthesized to demonstrate...

Antimicrobial resistance (AMR) affects multiple fields, including medicine, pharmacy, food safety, and animal husbandry, and poses a major threat to public health and economic development. Staphylococcus aureus has emerged as one of the most critical bacterial pathogens due to its widespread prevalence and significant genetic plasticity. This review outlines currently approved small-molecule drugs for clinical use and their me...