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Sustainable Production and In Vitro Giardicidal Activity of Bioactive Compounds Derived from Arthrospira PlatensisNARA Subscribed
Background Giardiasis remains a globally prevalent neglected parasitic disease, and limitations associated with conventional therapies highlight the need for alternative and complementary strategies. In this context, microalgae biocompounds have emerged as promising sources of antiparasitic agents. Objective This study aims to evaluate the in vitro preliminary screening activity (vital dye exclusion). Methods Aqueous extracts...
Migration-driven exposome reconfiguration: a predictive, preventive and personalized medicine perspective on cardiometabolic riskNARA Subscribed
Contemporary global migration, driven by socioeconomic instability, armed conflict, climate change, and political factors, has emerged as a major determinant of exposome reconfiguration and cardiometabolic vulnerability. Migrant populations are disproportionately exposed to cumulative environmental, psychosocial, behavioral, and cultural stressors that may contribute to chronic low-grade inflammation, neuroendocrine dysregulat...
Land use controls the spatiotemporal patterns of surface water quality of the Quadrilátero Ferrífero mineral province, BrazilNARA Subscribed
Surface water quality in the Quadrilátero Ferrífero, a mining province in southeastern Brazil, was evaluated by combining water quality indices (WQI), land use and land cover (LULC), and population data to identify spatial and seasonal influences on river chemistry. We analyzed 835 (rainy) and 845 (dry) samples and calculated WQI scores using established methods from the literature. The methods for calculating the WQI detected...
Living on the edge: agricultural land use increases genotoxic damage in amphibians on southern brazilian wetlandsNARA Subscribed
Southern Brazil is a key agricultural region in South America, where wetland ecosystems are increasingly impacted by irrigated rice cultivation. Amphibians are particularly sensitive to environmental contamination due to their permeable skin and biphasic life cycle, making them effective bioindicators of ecosystem health. This landscape forms a mosaic of croplands and natural habitats, exposing wildlife to agrochemical contami...
Climate change has intensified negative impacts on biodiversity through changes in precipitation patterns and rising global average temperatures. Semi-arid regions, such as parts of Northeastern Brazil, are particularly susceptible to these changes, with projections indicating that they will become hotter and drier, reducing the climatic suitability of several plant species. In this context, endemic and restricted-range specie...
Influence of Ketogenic Diet Lipid Composition on Anxiety-Like Behavior and Neurometabolic Profile in Healthy RatsNARA Subscribed
Ketogenic diets (KDs) modulate brain function, but how their fatty acid composition impacts behavior remains poorly understood. Male Wistar rats were fed a control diet (CD, n = 6), a classic ketogenic diet (CKD, n = 6) rich in saturated fatty acids (SAFAs), or a modified ketogenic diet (MKD, n = 6) enriched with polyunsaturated fatty acids (PUFAs) and DHA. After 100 days, both KDs induced similar ketosis and increased brain g...
Multiple factors associated with forest decline in the context of control measures for the pinewood nematodeNARA Subscribed
Forest decline is a complex phenomenon; however, there is often a tendency to oversimplify by attributing it to a single cause, neglecting the interaction of multiple factors. Ever since the detection of the pinewood nematode (PWN), Bursaphelenchus xylophilus , in Portugal (and in Europe) over two decades ago, pine wilt cases in the country have been primarily attributed to this pathogen, leading authorities to enforce strict...
The North Sea has been undergoing long‐term transformations driven by shifts in human activities and climate change, which have jointly reshaped the composition of marine communities. Despite existing studies, the functional mechanisms driving community changes remain poorly understood. Here, we analyzed a 43‐year time series of meso‐ and macro‐zooplankton (> 500 μ m) monitored at Helgoland Roads to assess long‐term changes in...