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Adaptive Variation Amid High Gene Flow Across a Broad Latitudinal Gradient in the Reef‐Building Honeycomb Worm, Sabellaria alveolataNARA Subscribed
Climate change is already altering, and will continue to reshape, the persistence and spatial structure of marine populations. Understanding metapopulation connectivity and local adaptation is therefore critical for identifying both vulnerable populations and those with adaptive resilience. We applied a seascape genomics approach to investigate connectivity patterns and adaptive responses in the honeycomb worm, Sabellaria alve...
Soil contamination assessment of a 19th-century abandoned Sb–Au mine in northern PortugalNARA Subscribed
Abandoned mines are among the main sources of long-term soil contamination, often leaving behind persistent concentrations of potentially toxic elements (PTE) that pose environmental and health risks. Ribeiro da Serra Sb–Au mine, in Portugal, active from 1858 to 1890, has left a significant environmental legacy. This study mapped the spatial distribution of mine processing residues, elemental characterisation distinguishing be...
Purpose The European Medicines Agency (EMA) guideline Declaration of Storage Conditions in the Product Information of Medicinal Products (CPMP/QWP/609/96/Rev.2) was last revised in 2007. Since then, advances in stability science, increased climatic variability, and evolving regulatory expectations have highlighted limitations in the framework, particularly the use of vague descriptors such as “room temperature” or “no special...
Co-60 gamma irradiation induces variation in F₃ watermelon resistance to Macrophomina phaseolinaNARA Subscribed
Gamma radiation has been employed to induce mutations in seeds and to develop disease-tolerant cultivars. This study aimed to assess resistance to Macrophomina phaseolina in F₃ watermelon ( Citrullus lanatus ) genotypes derived from seeds of the cultivar Sugar Baby irradiated with 200 Gy of Co-60 gamma rays. The experiment was conducted in a greenhouse using a completely randomised design, with 14 treatments, and five replicat...
Resistance of melon genotypes to Meloidogyne incognita and M. javanica: an approach based on genetic parameters estimated via REML/BLUPNARA Subscribed
Melon is one of the main vegetable crops grown in Brazil and is severely affected by root-knot nematodes of the genus Meloidogyne . The identification of resistance sources is therefore essential. Estimates of genetic parameters in breeding programs provide insight into the effects underlying the traits under evaluation. The objective of this study was to identify melon accessions resistant to Meloidogyne incognita and M. java...
Comparison of soil infestation and toothpick methods for Macrophomina species in melon plantsNARA Subscribed
In the northeast region of Brazil, melon production has been affected by root diseases caused by Macrophomina species. This study aimed to analyse the influence of inoculation methods using three Macrophomina species ( M. phaseolina , M. pseudophaseolina , and M. euphorbiicola ) on the expression of symptoms of root rot and branch decline in melon plants. Two inoculation methods were evaluated in greenhouse experiments: (1) in...
Micro‐Refuges or Ecological Traps: Context‐Dependent Effects of Rock Pools on Intertidal Biodiversity Across LatitudesNARA Subscribed
Aim We investigated how local‐scale environmental heterogeneity influences biodiversity patterns across broad biogeographic gradients, using intertidal microhabitats as a model system within one of the most environmentally stressful ecosystems on Earth. Location Intertidal habitats at 26 locations (two rocky shore sites per location) across six continents, spanning 98° of latitude (38°S to 60°N). Time Period 2019–2022. Major T...
Microneedles (MN) technology has emerged as a transformative tool within the biomedical field, offering innovative solutions to challenges in drug delivery, diagnostics, and therapeutic applications. This review article provides an in-depth exploration of the diverse perspectives and applications of MNs, shedding light on their pivotal role in shaping the future of biomedical research and clinical practice. It begins by elucid...
Motivation Here, we make available a second version of the BioTIME database, which compiles records of abundance estimates for species in sample events of ecological assemblages through time. The updated version expands version 1.0 of the database by doubling the number of studies and includes substantial additional curation to the taxonomic accuracy of the records, as well as the metadata. Moreover, we now provide an R packag...
Computational and experimental advances in liver-on-a-chip technology for cancer research: a systematic reviewNARA Subscribed
The integration of numerical simulations with Liver-on-a-Chip (LoC) technology offers an innovative approach for studying liver physiology and pathology, especially in the context of liver cancer. Numerical simulations facilitate the optimization of microfluidic devices’ design and deepen the understanding of fluid flow and mass transfer. However, despite significant advancements, challenges such as replicating the full comple...