Benign prostatic hyperplasia (BPH) is a prevalent urological disorder in aging men, frequently linked to hormonal fluctuations. Agomelatine (AGO), a melatonergic receptor agonist and serotonin 2C antagonist, has demonstrated anti-inflammatory and antioxidant properties. This study aimed to explore the potential of AGO in mitigating BPH induced by testosterone propionate (TP) in rats. Male rats received TP (5 mg/kg/day, subcuta...

In current applied research, innovative drug delivery systems have emerged as a strategy for managing plant diseases. The current study demonstrated the usefulness of three nano-drug delivery techniques for suppressing two fungal pathogens: Botrytis fabae and Alternaria alternata , which cause chocolate spot and minor disease leaf spot in Vicia faba plants. This work investigated the delivery of chitosan nanoparticles, carbon...

Around 20% of the human population is distressed. Previous studies have looked into the relationship between restraint immobilization stress (IS) and sexual behavior in male rats. The current study aimed to provide a brief explanation of the mechanisms that generated testicular injury with chronic IS and an attempt to evaluate the mechanisms and effects of vanillin as a novel protective agent. Forty-eight adult male albino rat...

This study evaluated the effects of dietary organic acid (OA) blend on hemato-immunological responses, reproduction capacity, gene expression, and histological features of red tilapia ( Oreochromis niloticus × O. mossambicus ) broodstock. Four diets were formulated, containing 0 (control), 2, 3, and 4 g OAs kg −1 . The diets were fed to triplicate groups ( n = 3) of red tilapia broodstock (75 ± 5.56 g( (mean ± standard deviati...

Background For years, the Kato-Katz (KK) technique has been considered the gold standard for diagnosing schistosomiasis. The aim of this study was to compare the effectiveness of our previously developed gold nanoparticle-based lateral flow test strip (AuNPs-LFTS) for diagnosing active Schistosoma mansoni with that of the commercially available point-of-care Circulating Cathodic Antigen detection (POC-CCA) kit. Methods In this...

The Nukhul Formation has been a point of controversy until now due to a lack of index fossils, varied facies modifications, and different time gaps. As a result, the calcareous nannofossils of the exposed Miocene rocks at Wadi Baba, west-central Sinai have been studied quantitatively for the first time. An important sequence of calcareous nannofossil bioevents has been recorded in the Nukhul Formation, including the FOs of Dis...

Acute lung injury is a serious condition accounting for the majority of acute respiratory failure. Bleomycin (BLM) is an antibiotic that was first described as a chemotherapeutic agent. 3,3′-methylenebis(1-ethyl-4-hydroxyquinolin-2(1 H )-one) was reported to have anti-inflammatory, anti-apoptotic, and anti-oxidative properties. The current work aimed to assess the possible protective effects and the mechanism of protection of...