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MEK inhibitor cobimetinib increases calreticulin and induces immune modulation in TNBCNARA Subscribed
Immunogenic cell death (ICD) can activate immune cells and potentiate the response to immunotherapy. The mitogen-activated protein kinase (MAPK) signaling pathway regulates the immune response and mediates T-cell receptor signaling. Activation of the MAPK signaling pathway decreases the levels of tumor-infiltrating lymphocytes in triple-negative breast cancer (TNBC) and is associated with worse survival. Here, we investigated...
Underwater image super-resolution plays an important role in marine exploration, as it aims to recover clearer and higher-resolution images from degraded low-resolution observations. However, in underwater environments, this task is particularly challenging due to non-uniform spectral attenuation and particle scattering. Underwater, red light fades quickly, leading to color distortion and loss of details. To address this while...