Pistacia lentiscus , from the Anacardiaceae family, is native to the Mediterranean region and best known for its aromatic resin, Chios mastic gum (CMG), which is exclusively produced on Chios Island, Greece. While the gum is the tree’s primary commercial product, various extracts from different P. lentiscus organs also hold potential applications due to their rich chemical profiles. This review assesses strategies to optimize...