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Calibrated Ecosystem Models Cannot Predict the Consequences of Conservation Management Decisions—ClarificationNARA Subscribed
Woodstock and Harris raise concerns about generalisations in our paper ‘Calibrated Ecosystem Models Cannot Predict the Consequences of Conservation Management Decisions’. They implied that our conclusions are invalidated by the exclusion of density dependent compensatory feedback and the existence of automated calibration approaches with overfitting penalties—claims that overlook the broader structural issues we identified. He...
Motivation Here, we make available a second version of the BioTIME database, which compiles records of abundance estimates for species in sample events of ecological assemblages through time. The updated version expands version 1.0 of the database by doubling the number of studies and includes substantial additional curation to the taxonomic accuracy of the records, as well as the metadata. Moreover, we now provide an R packag...
Calibrated Ecosystem Models Cannot Predict the Consequences of Conservation Management DecisionsNARA Subscribed
Ecosystem models are often used to predict the consequences of management interventions in applied ecology and conservation. These models are often high‐dimensional and nonlinear, yet limited data are available to calibrate or validate them. Consequently, their utility as decision‐support tools is unclear. In this paper, we calibrate ecosystem models to time series data from 110 different experimental microcosm ecosystems, eac...
Dispersal patterns of sandfish (Holothuria scabra) larvae in Manus Province, Papua New GuineaOA Marine
In many tropical nations, coastal communities seek to manage their sea cucumber fisheries by establishing locally managed marine areas on their traditional fishing grounds. These managed areas can protect spawning stocks, however the extent to which they help to replenish nearby sea cucumber fisheries is debated, as nothing is known about the scales at which sea cucumber larvae disperse. In this study, we used genetic parentag...
Green and sustainable solvents for biocatalytic oxidationsNARA Subscribed
Modeling total predation to avoid perverse outcomes from cat control in a data‐poor island ecosystemNARA Subscribed
Data‐hungry, complex ecosystem models are often used to predict the consequences of threatened species management, including perverse outcomes. Unfortunately, this approach is impractical in the many systems that have insufficient data to parameterize ecosystem interactions or reliably calibrate or validate such models. We devised a different approach composed of a minimum realistic model that guides decisions in data‐ and res...
A rich source of new therapeutics are natural products derived from modular non-ribosomal peptide synthetases (e. g. penicillins, daptomycin). Yet, efficient bioengineering of these often gigantic megaenzymes to generate natural product analogs is a major challenge. Using synthetic zippers, we have established a co-expression strategy that not only simplifies bioengineering, but rapidly increases the biocombinatorial potential...
Pro- and anti-inflammatory macrophages express a sub-type specific purinergic receptor profileNARA Subscribed
Extracellular nucleotides act as danger signals that orchestrate inflammation by purinergic receptor activation. The expression pattern of different purinergic receptors may correlate with a pro- or anti-inflammatory phenotype. Macrophages function as pro-inflammatory M1 macrophages (M1) or anti-inflammatory M2 macrophages (M2). The present study found that murine bone marrow-derived macrophages express a unique purinergic rec...
Discovery of a major QTL for root-knot nematode (Meloidogyne incognita) resistance in cultivated sweetpotato (Ipomoea batatas)NARA Subscribed
Key message Utilizing a high-density integrated genetic linkage map of hexaploid sweetpotato, we discovered a major dominant QTL for root-knot nematode (RKN) resistance and modeled its effects. This discovery is useful for development of a modern sweetpotato breeding program that utilizes marker-assisted selection and genomic selection approaches for faster genetic gain of RKN resistance. Abstract The root-knot nematode [Meloi...
Key message β-Carotene content in sweetpotato is associated with the Orange and phytoene synthase genes; due to physical linkage of phytoene synthase with sucrose synthase , β-carotene and starch content are negatively correlated. Abstract In populations depending on sweetpotato for food security, starch is an important source of calories, while β-carotene is an important source of provitamin A. The negative association betwee...
Cyclo(tetrahydroxybutyrate) production is sufficient to distinguish between Xenorhabdus and Photorhabdus isolates in ThailandNARA Subscribed
Summary Bacteria of the genera Photorhabdus and Xenorhabdus produce a plethora of natural products to support their similar symbiotic life cycles. For many of these compounds, the specific bioactivities are unknown. One common challenge in natural product research when trying to prioritize research efforts is the rediscovery of identical (or highly similar) compounds from different strains. Linking genome sequence to metabolit...
Trace element measurement for assessment of dog food safetyNARA Subscribed
Conservation fences are an increasingly common management action, particularly for species threatened by invasive predators. However, unlike many conservation actions, fence networks are expanding in an unsystematic manner, generally as a reaction to local funding opportunities or threats. We conducted a gap analysis of Australia's large predator‐exclusion fence network by examining translocation of Australian mammals relative...