Ana Prieto results 108
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Liver fibrosis and type 2 diabetes modulate postprandial incretin and glucagon responses in fatty liver diseaseNARA Subscribed
The study aims to characterize the secretion dynamics of glucagon-related peptides, including GLP-1, GIP, and GLP-2, across different stages of metabolic-associated steatotic liver disease (MASLD), while evaluating the impact of type 2 diabetes (T2D) on these hormonal responses. Thirty-four MASLD subjects were stratified according with the liver transient elastography (TE ≥ 9 kPa) and T2D in NF (no fibrosis, without T2D; n = 1...
Cylindrospermopsin is a potent cyanobacterial toxin of growing global concern due to its environmental persistence and broad toxicological profile. Despite increasing evidence of its toxic effects, knowledge of its toxicokinetics remains limited. This study integrates in silico ADMET predictions with in vitro microsomal assays using human and sex-stratified rat liver microsomes to characterize CYN biotransformation. In silico...
Consistent topsoil carbon density and driving factors in urban greenspaces and natural ecosystemsNARA Subscribed
Background Urban greenspaces have the potential to mitigate urban carbon footprints by storing soil organic carbon (SOC). Different management and plant communities associated with different types of urban greenspaces may hold contrasting SOC, as well as different proportions of particulate (POC) and mineral-associated organic carbon (MAOC). In addition, management could outweigh the effects of climate or soil properties as dr...
Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened Species by assessing the vulnerability of 256 marine megafauna species to 23 at‐sea threat...
Lithium dynamics. Global trends and local spatializationsNARA Subscribed