Background Although pediatric SARS-CoV-2 infection is usually mild; children with chronic conditions are at increased risk of severe disease. Myeloid Cell Leukemia-1 (MCL-1), a key regulator of mitochondrial apoptosis, is expressed as one anti-apoptotic isoform (MCL-1 L) and two pro-apoptotic isoforms (MCL-1 S and MCL-1ES), but their regulation in pediatric viral infections remains unclear. Methods and results We assessed MCL-...

High-throughput sequencing revealed a new emaravirus named clerodendrum yellow blotch virus (ClYBV), infecting Clerodendrum thomsoniae plants in São Paulo State, Brazil. Four genomic RNA segments (RNA1, RNA3, RNA4, and RNA5) were recovered, whereas RNA2 remained undetected. Phylogenetic analysis and pairwise comparisons based on amino acid sequences showed ClYBV is most closely related to redbud yellow ringspot-associated viru...

Community lineages of Staphylococcus aureus emerging in hospitals, such as CC398, have raised concerns. S. aureus CC398 isolates from bloodstream infections (BSI) and nasal colonization of hospitalized patients, during the COVID-19 pandemic, between March/2020 and September/2021, were characterized for antimicrobial susceptibility by disk diffusion test. Spa types and Sequence Type (ST) were analyzed by PCR/sequencing, and gen...

Southern Brazil is a key agricultural region in South America, where wetland ecosystems are increasingly impacted by irrigated rice cultivation. Amphibians are particularly sensitive to environmental contamination due to their permeable skin and biphasic life cycle, making them effective bioindicators of ecosystem health. This landscape forms a mosaic of croplands and natural habitats, exposing wildlife to agrochemical contami...

The ferruginous duricrust ( canga ) in the Iron Quadrangle (IQ), Minas Gerais, Brazil, occurs within the Campo Rupestre and presents remarkable levels of endemism and species richness. Despite the recognized importance of microorganisms for the maintenance of this ecosystem, current molecular-based studies reveal that both the taxonomic composition and the ecological functions of the canga microbiome are undiscovered. In this...

Bees are essential for ecosystem functioning, pollinating many wild and crop plant species. Predicting which species are most vulnerable to global changes, and how their loss may impact ecosystems and human well-being, is critical. Comprehensive information on bee response and effect traits is fundamental to these assessments. However, the Raunkiærian shortfall—insufficient trait data—remains significant for bees, particularly...

Ketogenic diets (KDs) modulate brain function, but how their fatty acid composition impacts behavior remains poorly understood. Male Wistar rats were fed a control diet (CD, n = 6), a classic ketogenic diet (CKD, n = 6) rich in saturated fatty acids (SAFAs), or a modified ketogenic diet (MKD, n = 6) enriched with polyunsaturated fatty acids (PUFAs) and DHA. After 100 days, both KDs induced similar ketosis and increased brain g...

The effects of global climate change on biodiversity and ecosystem functioning are unevenly distributed in the geographic space. Identifying sites more suitable to sustain biodiversity in a changing climate is essential to both species conservation and restoration strategies at different scales. Here, we map terrestrial climate‐resilient sites for biodiversity across Brazil to identify sites with greater chances of providing s...