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Rays of the family Rhinopteridae Jordan & Evermann, 1896 are highly migratory and widely distributed in warm tropical and temperate waters. Along the Brazilian coast, the presence of two species has been recorded: Rhinoptera bonasus Mitchill, 1815 and Rhinoptera brasiliensis Müller, 1836. These stingrays are commonly caught as bycatch in trawl fisheries, however, the two species lack distinctive external morphological features...
Cetaceans are highly adapted marine mammals whose survival depends on precise auditory and echolocation systems. Therefore, disease processes affecting these systems, including parasitic infections pose significant morbidity and may result in stranding and death. Here, we describe the pathologic and parasitological findings in an adult, male melon-headed whale ( Peponocephala electra ) stranded dead on the Brazilian coast. The...
Lupeol as a modulator of bacterial resistance mediated by the MepA efflux pump in Staphylococcus aureusNARA Subscribed
Bacterial resistance constitutes one of the main threats to global public health, driving the search for therapeutic strategies capable of restoring the effectiveness of antimicrobials. Among the mechanisms involved, efflux pumps stand out, reducing the intracellular concentration of drugs and contributing to multidrug resistance. In this context, inhibitors of these pumps emerge as a promising approach, as they increase the i...
Multiform glioblastoma (GBM) is the most aggressive primary brain tumor, associated with high heterogeneity, treatment resistance, and poor survival. Temozolomide (TMZ), although the main chemotherapeutic agent used, shows limited efficacy due to low solubility, chemical instability, and acquired resistance. In this context, nanostructured systems can enhance their antitumor efficacy. This study aimed to develop and characteri...
Moisture transport from the tropics to the subtropics by the low‐level jets (LLJs) east of the Andes crosses the Pantanal region, located in the Upper Paraguay River Basin (UPRB), a biome strongly dependent on remote moisture sources. This study investigates the climatological contribution of these LLJs to moisture transport into the UPRB and their influence on regional precipitation. For this purpose, LLJs and Lagrangian mois...