The lima bean ( Phaseolus lunatus L.) is a legume of high agronomic and nutritional importance, particularly for smallholder farming in northeastern Brazil. The breeding program at the Federal University of Piauí (UFPI, Brazil) developed lines from biparental crosses, selecting traits of agronomic relevance for crop improvement, such as determinate growth habit, earliness, and yield. This study evaluated the genetic diversity...

Intensive cucumber cultivation favors the occurrence of pests, particularly Tetranychus urticae (Koch) (Acari: Tetranychidae), which causes damage to leaf tissues, impairing photosynthesis and cellular integrity. Management of this pest is commonly based on chemical control; however, this strategy may intensify oxidative stress in plants. In this context, biological control emerges as a sustainable alternative. This study aime...

Variable resistance to Haemonchus contortus infection and the associated immune mechanisms have been investigated and characterized in different sheep breeds adapted to tropical climates. In a recent study, we compared the local immune responses of the resistant Santa Inês with those of the susceptible White Dorper and Texel sheep breeds under chronic haemonchosis, and evaluated the correlations of immune-related transcripts a...

HDV has a high genetic diversity among isolates and a high capacity to accumulate mutations over time. The mechanisms involved in the clinical progression of HDV are not fully elucidated. Few studies relate mutations to clinical implications, which makes this variable extremely relevant for research into HDV-3, a genotype associated with worse clinical progression. The aim of this study was to analyze mutations in complete gen...

Bacterial resistance constitutes one of the main threats to global public health, driving the search for therapeutic strategies capable of restoring the effectiveness of antimicrobials. Among the mechanisms involved, efflux pumps stand out, reducing the intracellular concentration of drugs and contributing to multidrug resistance. In this context, inhibitors of these pumps emerge as a promising approach, as they increase the i...

Multiform glioblastoma (GBM) is the most aggressive primary brain tumor, associated with high heterogeneity, treatment resistance, and poor survival. Temozolomide (TMZ), although the main chemotherapeutic agent used, shows limited efficacy due to low solubility, chemical instability, and acquired resistance. In this context, nanostructured systems can enhance their antitumor efficacy. This study aimed to develop and characteri...

The Amazonian species paricá ( Schizolobium parahyba var. amazonicum ( Huber ex Ducke ) Barneby ) accumulates cadmium (Cd) primarily in the roots, but the lack of understanding of gene modulation in response to this metal and the phytohormonal mechanisms complicates its relevance in the rehabilitation of degraded areas. Therefore, the present study aims to examine the expression of the CYP 85 A 2 and BZR1 genes, precursors of...